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Initial dose: 0.5 mg orally 3 times a day
What happens if I overdose?




More Pregnancy Warnings

Keep track of the amount of medicine used from each new bottle. Alprazolam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Do not drink alcohol while taking alprazolam. This medication can increase the effects of alcohol. This medicine may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.





Alprazolam can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using this medicine.

What should I avoid while taking alprazolam?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal. Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.
Before taking this medicine

Initial dose: 0.25 mg orally 2 to 3 times a day in elderly or debilitated patients

Alprazolam may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Extended-release tablets:
User Reviews

if you are allergic to alprazolam or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

This dose may be gradually increased every 3 to 4 days if needed and tolerated.



Do not use alprazolam if you are pregnant. This medicine can cause birth defects or life-threatening withdrawal symptoms in a newborn.

nefazodone;

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Usual Adult Dose for Anxiety:

The daily dose may be gradually increased by no more than 1 mg every 3 to 4 days if needed and tolerated.
Average Dose: Studies in the treatment of depression have reported an average effective dose of 3 mg orally daily in divided doses
Because of increased sensitivity to benzodiazepines in elderly patients, alprazolam at daily doses greater than 2 mg meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Smaller doses may be effective as well as safer. Total daily doses should rarely exceed suggested maximums.
Important information

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Drinking alcohol with this medicine can cause side effects.
Alprazolam may also be used for purposes not listed in this medication guide.
You should not take alprazolam if you have:
fluvoxamine;
Support Group Q & A

What other drugs will affect alprazolam?


Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It affects chemicals in the brain that may be unbalanced in people with anxiety.
Usual Geriatric Dose for Depression:

depressed mood, thoughts of suicide or hurting yourself;

Usual Adult Dose for Depression:

a history of depression or suicidal thoughts or behavior;
Breastfeeding Warnings
Professional
Maintenance dose: 1 to 10 mg once a day
Initial dose: 0.25 mg orally 2 to 3 times a day in elderly or debilitated patients


Overview
Initial dose: 0.5 to 1 mg once a day

Usual Geriatric Dose for Anxiety:


Patient Tips
Tell your doctor about all your current medicines and any you start or stop using, especially:
Initial dose: 0.5 mg orally 3 times a day

Usual Geriatric Dose for Panic Disorder:



Alprazolam is used to treat anxiety disorders , panic disorders , and anxiety caused by depression.
Do not swallow the orally disintegrating tablet whole. Allow it to dissolve in your mouth without chewing.


slurred speech, lack of balance or coordination;
Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Maintenance dose: May increase up to maximum daily dose of 4 mg in divided doses


Do not stop using alprazolam suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using alprazolam.


Alprazolam is not approved for use by anyone younger than 18 years old.
Immediate-release tablets, orally disintegrating tablets, oral concentrate:

You should not use alprazolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to alprazolam or similar medicines (Valium, Ativan, Tranxene, and others).
Store at room temperature away from moisture and heat.

Dosage


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confusion, agitation, hostility, hallucinations;

Maintenance dose: 1 to 10 mg per day in divided doses


See also: Dosage Information (in more detail) What happens if I miss a dose?
Immediate-release tablets, orally disintegrating tablets, oral concentrate:


open-angle glaucoma;



This dose may be gradually increased if needed and tolerated.


See also: Side effects (in more detail) Alprazolam dosing information
Immediate-release tablets, orally disintegrating tablets:
If you use this medicine long-term, you may need frequent medical tests.


Do not use alprazolam if you are pregnant. This medicine can cause birth defects. Your baby could also become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy while you are taking this medicine.
Grapefruit and grapefruit juice may interact with alprazolam and lead to unwanted side effects. Discuss the use of grapefruit products with your doctor.
pounding heartbeats or fluttering in your chest.



kidney or liver disease (especially alcoholic liver disease);
To make sure this medicine is safe for you, tell your doctor if you have:
Maximum Dose: Studies in the treatment of depression have reported to have used 4.5 mg orally daily in divided doses as a maximum.
cimetidine;
a history of drug or alcohol addiction; or

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use alprazolam only for the indication prescribed.

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Do not crush, chew, or break an extended-release tablet . Swallow it whole.

Usual Adult Dose for Panic Disorder:

uncontrolled muscle movements, tremor, seizure (convulsions); or
It is dangerous to purchase alprazolam on the Internet or from vendors outside the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. The sale and distribution of alprazolam outside the U.S. does not comply with the regulations of the Food and Drug Administration (FDA) for the safe use of this medication.


Because of increased sensitivity to benzodiazepines in elderly patients, alprazolam at daily doses greater than 2 mg meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Smaller doses may be effective as well as safer. Total daily doses should rarely exceed suggested maximums.
digoxin;

This dose may be gradually increased if needed and tolerated.
Immediate-release tablets, orally disintegrating tablets:
The sedative effects of alprazolam may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking alprazolam.

Take alprazolam exactly as prescribed by your doctor. Follow all directions on your prescription label. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in treating your symptoms.
This dose may be gradually increased every 3 to 4 days if needed and tolerated.

Mean dose employed: 3 to 6 mg once a day
Misuse of habit-forming medicine can cause addiction, overdose, or death. Selling or giving away this medicine is against the law.

Xanax: 12 Things You Should Know
More about alprazolam Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Espanol 841 Reviews - Add your own review/rating Consumer resources Alprazolam Alprazolam extended-release tablets Alprazolam orally disintegrating tablets Alprazolam solution Alprazolam Oral (Advanced Reading) Other brands: Xanax , Xanax XR , Alprazolam Intensol , Niravam Professional resources Alprazolam (AHFS Monograph) More (5) » Related treatment guides Anxiety Borderline Personality Disorder Panic Disorder Dysautonomia Depression More (1) »
Slideshow
seizures or epilepsy;
Side Effects
Alprazolam may be habit-forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Drug Images


Call your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.
Initial dose: 0.25 mg orally 2 to 3 times a day in elderly or debilitated patients
This dose may be gradually increased if needed and tolerated.
Immediate-release tablets, orally disintegrating tablets, oral concentrate:
Alprazolam side effects
Because of increased sensitivity to benzodiazepines in elderly patients, alprazolam at daily doses greater than 2 mg meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Smaller doses may be effective as well as safer. Total daily doses should rarely exceed suggested maximums.
Where can I get more information?
The daily dose may be gradually increased by no more than 1 mg every 3 to 4 days.

Initial dose: 0.5 mg once a day preferably in the morning

Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.

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ritonavir or other medicines to treat HIV or AIDS; or
Initial dose: 0.25 to 0.5 mg orally 3 times a day
Immediate-release tablets, orally disintegrating tablets, oral concentrate:
memory problems; or



This list is not complete. Other drugs may interact with alprazolam, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Your pharmacist can provide more information about alprazolam.
asthma or other breathing disorder;

Generic Name: alprazolam (al PRAY zoe lam) Brand Names: Niravam, Xanax, Xanax XR
Common alprazolam side effects may include:
narrow-angle glaucoma;


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racing thoughts, increased energy, unusual risk-taking behavior;


feeling anxious early in the morning.
if you are also taking itraconazole or ketoconazole; or
drowsiness, feeling tired;

Extended-release tablets:

Get emergency medical help if you have signs of an allergic reaction to alprazolam : hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This dose may be gradually increased if needed and tolerated.
Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking a sleeping pill, narcotic pain medicine, prescription cough medicine, a muscle relaxer, or medicine for anxiety, depression, or seizures.


if you also use a narcotic (opioid) medication.

Call your doctor at once if you have:

Mean dose employed: 5 to 6 mg per day in divided doses
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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