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kidney disease (or if you are on dialysis);


The efficacy has not been established if started more than 72 hours after onset of signs and symptoms.
1 g orally every 8 hours for 7 days
Usual Adult Dose for CMV Prophylaxis:

Valtrex can be harmful to the kidneys, and these effects are increased when it is used together with other medicines that can harm the kidneys. Tell your doctor about all other medications you are using. You may need dose adjustments or special tests when taking certain medications together with Valtrex.

Side Effects

See also: Side effects (in more detail) What other drugs will affect Valtrex?

More Pregnancy Warnings

Some herpes infections need to be treated for longer than others. Use this medicine for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Skipping doses may increase the risk of your virus becoming resistant to antiviral medicine.
Genital herpes:

HIV-infected host with CD4 count 100 cells/mm3 or more: 500 mg orally twice a day


Slideshow
Usual Adult Dose for Herpes Simplex -- Mucocutaneous/Immunocompromised Host:

feeling weak or tired;

Valtrex can harm your kidneys. This effect is increased when you also use certain other medicines, including: antivirals, chemotherapy, injected antibiotics, medicine for bowel disorders, medicine to prevent organ transplant rejection, injectable osteoporosis medication, and some pain or arthritis medicines (including aspirin, Tylenol, Advil, and Aleve).

stomach pain, bloody diarrhea, vomiting; or

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


red spots on the skin (not related to herpes or chickenpox);

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

You may take Valtrex with or without food.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
rash; or
problems with speech;
Lesions caused by herpes viruses should be kept as clean and dry as possible. Wearing loose clothing may help to prevent irritation of the lesions.
You should not use Valtrex if you are allergic to valacyclovir or acyclovir (Zovirax).
Avoid sexual intercourse or use a latex condom to help keep you from spreading the virus to others. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent the spread of infection.

Efficacy beyond 8 months has not been established in discordant couples.
unusual bleeding (nosebleeds, bleeding gums);



Most effective if started within 48 hours of onset of rash. The efficacy has not been established if started more than 72 hours after onset of rash.
Valtrex dosing information
Usual Pediatric Dose of Valtrex for Herpes Simplex Labialis:

Genital herpes in HIV-infected host:
Safety and efficacy beyond 6 months have not been established in HIV-infected patients.


Valtrex side effects
What happens if I overdose?

hallucinations (seeing or hearing things that are not real);


Valacyclovir can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.


Immunocompetent host: 1 g orally once a day

Therapy should be started at the first sign of a genital herpes episode. The efficacy has not been established if started more than 24 hours after onset of signs and symptoms.





Therapy should be initiated at the earliest sign of chickenpox, no later than 24 hours after onset of rash.
Call your doctor at once if you have:
Common Valtrex side effects may include:
First episode: 1 g orally twice a day for 7 to 10 days
It is not known whether Valtrex will harm an unborn baby. However, herpes virus can be passed from an infected mother to her baby during childbirth. If you have genital herpes , it is very important to prevent herpes lesions during your pregnancy, so that you do not have a genital lesion when your baby is born.
Before taking Valtrex, tell your doctor if you have HIV/AIDS, a weak immune system, kidney disease (or if you are on dialysis), or if you have had a kidney or bone marrow transplant.

Alternative dose for immunocompetent host with a history of 9 or fewer recurrences per year: 500 mg orally once a day
red or pink urine, little or no urination;
See Other Comments for extemporaneous preparation of oral suspension.
fever, pale skin;
In renal transplant recipient: 2 g orally 4 times a day

Consumer resources Valtrex Valtrex (Advanced Reading) Professional resources Valtrex (AHFS Monograph) Valtrex (FDA) Related treatment guides Cold Sores Herpes Simplex, Suppression Varicella-Zoster Herpes Simplex, Mucocutaneous/Immunocompromised Host Cytomegalovirus Infection More (3) »

Dosage

Recurrent episode: 1 g orally twice a day for 5 to 14 days
What is Valtrex?




swelling in your face, hands, or feet.

Stop taking Valtrex and call your doctor right away if you have any signs of a serious side effect that can harm red blood cells, such as: fever, easy bruising or bleeding, red spots on the skin (not related to herpes or chickenpox), bloody diarrhea, vomiting, pale or yellowed skin, weakness, fainting, or urinating less than usual or not at all.
headache;

User Reviews
2 g orally every 12 hours for a total of 2 doses (4 g)
See also: Dosage Information (in more detail) What happens if I miss a dose?


Take Valtrex exactly as it was prescribed for you. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Usual Adult Dose for Herpes Simplex -- Suppression:
Generic Name: valacyclovir (val a SYE kloe veer) Brand Names: Valtrex
Interactions
Stop taking Valtrex and call your doctor right away if you have any of the following signs of a serious side effect that can harm red blood cells:

Recurrent episode: 500 mg orally twice a day for 3 days




Pricing & Coupons



Chronic suppression of recurrent genital herpes:
Valtrex is used to treat infections caused by herpes viruses, including genital herpes , cold sores , and shingles (herpes zoster) in adults.
Usual Pediatric Dose of Valtrex for Varicella-Zoster:
Usual Adult Dose for Herpes Simplex -- Mucocutaneous/Immunocompetent Host:

2 to less than 18 years: 20 mg/kg orally 3 times a day for 5 days

To make sure Valtrex is safe for you, tell your doctor if you have:



Other drugs may interact with valacyclovir, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.




What should I avoid while taking Valtrex?
a seizure (convulsions); or
First episode: 1 g orally twice a day for 7 to 14 days
The efficacy has not been established if started more than 72 hours after onset of signs and symptoms.
Drink plenty of water while you are taking Valtrex to keep your kidneys working properly.
Treatment with Valtrex should be started as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters).
Usual Adult Dose of Valtrex for Herpes Zoster:
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Valtrex only for the indication prescribed.

tired feeling.


a history of kidney transplant or bone marrow transplant.
Store Valtrex tablets at room temperature away from moisture and heat.
What's That? 10 Of The Most Common Skin Conditions

The use of Valtrex for the treatment of initial and recurrent genital herpes in HIV-infected patients is not approved by the FDA.


confusion, aggression, or you feel shaky or unsteady;
Overview
Add to My Med List
The use of Valtrex for cytomegalovirus prophylaxis is not approved by the FDA.

Your pharmacist can provide more information about Valtrex.
Valtrex will not cure herpes and will not prevent you from spreading the virus to other people. However, this medicine can lessen the symptoms of an infection.
nausea, stomach pain;
Do not give this Valtrex to a child without medical advice.
Valtrex is used to treat cold sores in children who are at least 12 years old, or chickenpox in children who are at least 2 years old.

Professional
Drug Images
More about Valtrex (valacyclovir) Side Effects During Pregnancy or Breastfeeding Dosage Information Drug Images Drug Interactions Support Group Pricing & Coupons En Espanol 193 Reviews - Add your own review/rating Generic Availability



Important information
Therapy should be started at the first sign of a genital herpes episode. The efficacy has not been established if started more than 24 hours after onset of signs and symptoms.
Safety and efficacy beyond 1 year have not been established in immunocompetent patients.

kidney problems--little or no urination, painful or difficult urination, swelling in your feet or ankles, feeling tired or short of breath.
Therapy should be started at the earliest sign of a cold sore (such as tingling, burning, or itching).
Start taking Valtrex as soon as possible after the first appearance of symptoms (such as tingling, burning, blisters). This medicine might not be as effective if you first start taking it 1 or 2 days after the start of your symptoms.




Usual Adult Dose of Valtrex for Herpes Simplex Labialis:
Breastfeeding Warnings

Chickenpox in immunocompetent host:
Taking this medicine will not prevent you from passing genital herpes to other people. Herpes infections are contagious and you can infect other people even while you are taking with Valtrex.

Get emergency medical help if you have signs of an allergic reaction to Valtrex : hives; difficult breathing; swelling of your face, lips, tongue, or throat.



12 years or older: 2 g orally every 12 hours for a total of 2 doses (4 g)
Therapy should be started at the earliest sign of a cold sore (such as tingling, burning, or itching).
Reduction of transmission of genital herpes in immunocompetent host with a history of 9 or fewer recurrences per year: 500 mg orally once a day for the source partner
Before taking this medicine
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Where can I get more information?
HIV/AIDS, or other conditions that can weaken the immune system; or
Valtrex (valacyclovir) is an antiviral drug. It slows the growth and spread of the herpes virus to help the body fight the infection.
Support Group Q & A
Maximum dosage: 1 g orally 3 times a day
How should I take Valtrex?
Side effects may be more likely in adults who are 65 or older.
Do not share this medicine with another person, even if they have the same symptoms you have.

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