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Usual Adult Dose for Benign Prostatic Hyperplasia:

Some medicines can cause unwanted or dangerous effects when used with tadalafil. Tell your doctor about all your current medicines, especially riociguat (Adempas).


See also: Dosage Information (in more detail) What happens if I miss a dose?

Do not take tadalafil if you are also using a nitrate drug for chest pain or heart problems. This includes nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite ("poppers"). Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.


If you take tadalafil every day and you miss a dose, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
headache;


-5 mg orally once a day at approximately the same time, without regard to timing of sexual activity

To make sure tadalafil is safe for you, tell your doctor if you have any of these other conditions:
Before taking this medicine




Once daily use for BPH:

Usual Adult Dose for Pulmonary Hypertension:
Interactions
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Tadalafil side effects
Tadalafil may also be used for purposes not listed in this medication guide.
Do not break or split a Cialis tablet. Swallow it whole.

Important information
Grapefruit and grapefruit juice may interact with tadalafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking this medicine.


Tadalafil can decrease blood flow to the optic nerve of the eye, causing sudden vision loss. This has occurred in a small number of people taking Viagra or other drugs similar to tadalafil. Most of these people also had certain pre-existing eye problems or risk factors for blood vessel disorders (such as heart disease, diabetes, high blood pressure, high cholesterol, coronary artery disease, smoking, or being over 50 years old). It is not clear whether tadalafil is the actual cause of vision loss.
Stop using tadalafil and get emergency medical help if you have:

liver or kidney disease (or if you are on dialysis);
Once daily use for ED and Benign Prostatic Hyperplasia (BPH):



Comments: The incremental benefit of this drug decreases from 4 weeks until 26 weeks. The incremental benefit of this drug beyond 26 weeks is unknown.

shortness of breath;


a recent heart attack (within the past 90 days);
an antibiotic or antifungal medicine;



What other drugs will affect tadalafil?
antiviral medicine to treat hepatitis C or HIV/AIDS;




seizure (convulsions); or
What happens if I overdose?
More about tadalafil Side Effects During Pregnancy Dosage Information Drug Interactions Support Group En Espanol 383 Reviews - Add your own review/rating Consumer resources Tadalafil Tadalafil (Advanced Reading) Other brands: Cialis , Adcirca Professional resources Tadalafil (AHFS Monograph) Tadalafil (Wolters Kluwer) Related treatment guides Erectile Dysfunction Benign Prostatic Hyperplasia Pulmonary Hypertension
diarrhea;

Use as needed for ED:

-Maintenance dose: 2.5 to 5 mg orally once a day based on individual efficacy and tolerability.
Use: Treatment of erectile dysfunction (ED)

User Reviews
-40 mg orally once a day
Contact your doctor or seek emergency medical attention if your erection is painful or lasts longer than 4 hours. A prolonged erection (priapism) can damage the penis.

Professional
sinus pain, sore throat; or
a bleeding disorder such as hemophilia;
a stomach ulcer;
Tadalafil can be taken with or without food.
Support Group Q & A

Drinking alcohol with this medicine can cause side effects.
Usual Adult Dose for Erectile Dysfunction:


More Pregnancy Warnings

retinitis pigmentosa (an inherited condition of the eye);

irregular heartbeat;
Your pharmacist can provide more information about tadalafil.

angina (chest pain), high or low blood pressure;
-Initial dose: 2.5 mg orally once a day at approximately the same time, without regard to timing of sexual activity
What should I avoid while taking tadalafil?

Dosage

Common tadalafil side effects may include:


a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;
Once a day use for ED:
-Maintenance dose: 5 to 20 mg orally once a day, as needed, prior to sexual activity based on individual efficacy and tolerability
erection is painful or lasts longer than 4 hours (prolonged erection can damage the penis);

Store at room temperature away from moisture and heat.

Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
How should I take tadalafil?
vision changes or sudden vision loss; or
Adcirca (R):
Do not take Cialis for erectile dysfunction if you are taking Adcirca for pulmonary arterial hypertension.


It is not known whether tadalafil passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
heart disease or heart rhythm problems, coronary artery disease;

Comment: Consider that this drug has shown to improve erectile dysfunction up to 36 hours following dosing, when used as needed.



Do not take tadalafil if you are also using a nitrate drug for chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and some recreational drugs such as "poppers". Taking tadalafil with a nitrate medicine can cause a sudden and serious decrease in blood pressure.

a light-headed feeling, like you might pass out.


Stop using tadalafil and get emergency medical help if you have sudden vision loss.

Also call your doctor right away if you have:



muscle pain.










Add to My Med List
This list is not complete. Other drugs may interact with tadalafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.


a physical deformity of the penis (such as Peyronie's disease); or
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).



seizure medicine.



Slideshow

Generic Name: tadalafil (ta DAL a fil) Brand Names: Adcirca, Cialis
Tadalafil is usually taken only once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.


See also: Side effects (in more detail) Tadalafil dosing information



drugs to treat high blood pressure or a prostate disorder; or


if you have been told you should not have sexual intercourse for health reasons.

Use: Treatment of the signs and symptoms of benign prostatic hyperplasia (BPH)
a recent history (in the past 6 months) of a stroke, or congestive heart failure;


-5 mg orally once a day at approximately the same time, without regard to timing of sexual activity

Overview
Tell your doctor about all your current medicines and any you start or stop using, especially:
-5 mg orally once a day at approximately the same time


Cialis can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill. Follow your doctor's instructions.


This medicine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.



What is tadalafil?
-5 mg orally once a day at approximately the same time, for up to 26 weeks
Side Effects
If tadalafil is used as needed, you are not likely to be on a dosing schedule.

ringing in your ears, or sudden hearing loss;
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use tadalafil only for the indication prescribed.

heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
Once daily use for ED and BPH:
swelling in your hands, ankles, or feet;

Do not take Cialis while also taking Adcirca, unless your doctor tells you to.
For erectile dysfunction, take Cialis just before sexual activity but not more than once per day.
You should not take tadalafil if you are allergic to it, or:

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect of tadalafil.
-Initial dose: 10 mg orally once a day, as needed, prior to sexual activity

Tadalafil relaxes muscles found in the walls of blood vessels and increases blood flow to particular areas of the body.
Get emergency medical help if you have any signs of an allergic reaction to tadalafil: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Where can I get more information?
Concomitant administration with finasteride:





Tadalafil under the name of Cialis is used to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate). Another brand of tadalafil is Adcirca, which is used to treat pulmonary arterial hypertension and improve exercise capacity in men and women.

Cialis: 7 Important Things You Need to Know

Comment: Dividing the 40 mg dose over the course of the day is not recommended.

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